236 H1 Antihistamines Influence on Pro-inflammatory Cytokines Level in Patients With Allergic Rhinitis
نویسندگان
چکیده
regional variations. That’s why; the allergen profiles of the regions must be determined and the dermal Prick tests must be prepared accordingly. Mostly grass and cereal mixtures and mites are responsible from the allergic rhinitis cases due to our observations in our clinic. The other important allergens that are linked to the flora and climate of the region are olive and the cockroaches. High asthma prevalence in people living in shanties and in housewives may be due to exposure to house dust mites.
منابع مشابه
In Vivo Anti-Inflammatory Effect of H1 Antihistamines in Allergic Rhinitis: A Randomized Clinical Trial.
BACKGROUND Allergic rhinitis is characterized by a chronic inflammation of nasal mucosa and represents a risk factor for asthma occurrence. H1 antihistamines reduce the symptoms of rhinitis, but some compounds may have anti-inflammatory properties. AIMS We evaluated the plasma level of some cytokines in patients with persistent allergic rhinitis (PAR) and their evolution after a 4-week treatm...
متن کاملDecreased serum level of lipoxin A4 (LXA4) may contribute to the pathogenesis of allergic rhinitis
Background: Rhinitis is a prevalent chronic inflammatory disease of the nasal mucosa. Arachidonic acid-derived lipoxin A4 (LXA4) has long been recognized to exert crucial anti-inflammatory and pro-resolving effects on inflammatory responses through a specific receptor named formyl peptide receptor-2 (FPR2). This study aimed to determine the serum level of LXA4 as well as the relative mRNA expre...
متن کاملImmunology of the Upper Airway and Pathophysiology and Treatment of Allergic Rhinitis
• The immune system protects the organism from infectious microbes and avoids responses that produce damage to host tissues. • The immune system is divided into the innate and adaptive systems. The adaptive immune system recognizes different specific antigens, adapts to changing environments, and provides immunologic memory. • The innate immune system includes all aspects of the host defense me...
متن کامل237 International Survey on the Management of Allergic Rhinitis by Physicians and Patients (ISMAR)
in healthy volunteers. Levocetirizine reduces plasmatic level of IL-6 (1.19 versus 1.006, P 1⁄4 0.0097) and IL-8 (8.90 versus 6.90, P 1⁄4 0.0003) after 4 weeks treatment, while Desloratadine has influence only IL-6 level (1.68 versus 1.36, P 1⁄4 0.0038). The intergroup analysis revealed no significant difference between these 2 drugs regarding IL-6 (P 1⁄4 0.36) and IL-8 (P 1⁄4 0.25). Conclusion...
متن کاملTh17 responses are not altered by natural exposure to seasonal allergens in pollen-sensitive patients
BACKGROUND Allergic rhinitis affects 10-30 % of the global population and this number is likely to increase in the forthcoming years. Moreover, it commonly co-exists with allergic asthma as a chronic allergic respiratory syndrome. While the involvement of Th2 cells in allergy is well understood, alterations of pro-inflammatory Th17 responses remain poorly characterized. The aim of our study was...
متن کامل